Award
Congratulations to the winners of NextEpoch 2024
Lab update celebrating trainees recognized through the NextEpoch 2024 program.
News & media
Papers, coverage, and lab milestones.
A running record of work coming out of the lab — new publications, external press, talks, and the people moving on to next things.
PNAS
Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure
Collaboration with Gad Frankel's group at Imperial College London — an RNA structural element drives recurrent antibiotic resistance.
Nature Communications
An intranasal ASO therapeutic targeting SARS-CoV-2
Collaboration with Anders Näär's group on an inhaled antisense oligonucleotide that targets a structured region of the SARS-CoV-2 genome.
Tools
DREEM web interface available
A web-based interface for chemical probing analysis from raw sequencing files, developed with Joseph Yesselman's group.
Nature Communications
Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells
The lab's whole-genome RNA structure work on SARS-CoV-2 appeared in Nature Communications.
Lab milestone
The lab moved to the New Research Building at Harvard Medical School
Rouskin Lab settled into NRB 930 at HMS, our home base for the next phase of the lab.
Press
The New York Times covers SARS-CoV-2 whole-genome RNA structure work
External coverage of the lab's SARS-CoV-2 RNA structure mapping.
Press
Whitehead News: HIV genome bends over backwards to control its own gene expression
External coverage of alternative HIV RNA structures and their role in viral gene regulation.
Nature
Determination of RNA structural diversity and its role in HIV-1 RNA splicing regulation
The lab's flagship paper on alternative RNA structures in HIV-1 was published in Nature.
Lab milestone
Phil became Dr. Phil
Lab celebration for Phil Tomezsko's successful thesis defense.
Lab milestone
Congratulations to Tammy for starting graduate school at Harvard MCO
Trainee milestone — onwards to grad school.
Lab milestone
New UROPs joined the lab
The lab welcomed new undergraduate researchers from MIT's UROP program.
Lab milestone
Sherry Nyeo joined the lab as a UROP
Sherry worked on alternative splicing and structure of SMN1 and SMN2.
Lab milestone
Stuti Khandwala joined the lab as a UROP
Stuti worked on tau alternative structure and splicing with Tammy.